Plenary Lecture at the Santen Vision Summit in Bangkok, Thailand, January 2020. "Bacterial Ocular Infection in Asia: A Physician's Journey"

In this video, Dr Cordelia Chan speaks on eye infections, with special emphasis on bacterial infections of the eye. She talks about how the management of bacterial keratitis in Asia has changed over the years, and covers the problem of the overuse of antibiotic eye drops and antibiotic resistance. This talk chronicles Dr Chan's journey as a subspecialist in Cornea and External Eye Disease, from her days as a young eye doctor in Singapore in the early 1990s, to the present. 

Patients who have had a painful red eye in the past, with conjunctivitis or a corneal ulcer from contact lens wear, may find this video of interest. 

Important disclaimer:  Video copyright belongs to Santen Pharmaceutical Asia Pte. Ltd. and permission has been granted to post this video  

To SMILE or not to SMILE?

Small incision lenticule extraction (SMILE) is one of the laser vision correction procedures for short-sightedness (myopia) and astigmatism available in Singapore and around the world. Dr Cordelia Chan was one of the first surgeons in Singapore to perform SMILE in 2012. In this talk she gives her views on the procedure, and shares her experience with both SMILE and LASIK. So is SMILE better than LASIK? Watch the video to find out. 

Ophthalmic Magazine Publications

The Declining Incidence of Post-Lasik Ectasia

The Changing Landscape of Keratoconus Management

Lasik: Now, Better Than Ever

The Evolution of Pterygium Surgery

Website On Eye Rubbing

This is an important website on Keratoconus and Eye Rubbing for both patients and ophthalmologists.

The website was created to highlight the deleterious effects of eye rubbing on the cornea, and to link it to keratoconus genesis and progression in an evidence-based manner. 

This website was designed and created by the ophthalmologists of the Rothschild Foundation, Paris, France, with Dr Cordelia Chan as the Special Editing Consultant. 

If you have keratoconus, high astigmatism, or have a habit of rubbing your eyes, this website is for you. It also gives useful tips on how to avoid eye rubbing and provides alternatives and less harmful techniques of eye rubbing for those who really feel the need to touch their eyes. 


Research Publications

Highlights from the 2019 International Myopia Summit on 'controversies in myopia'.
Wong CW, Foo LL, Morjaria P, Morgan I, Mueller A, Davis A, Keys D, He M, Sankaridurg P, Zhu JF, Hendicott P, Tan D, Saw SM, Cheng CY, Lamoureux EL, Crowston JG, Gemmy Cheung CM, Sng C, Chan C, Wong D, Lee SY, Agrawal R, Hoang QV, Su X, Koh A, Ngo C, Chen H, Wu PC, Chia A, Jonas JB, Wong TY, Ang M.
Br J Ophthalmol. 2020 Aug 18:bjophthalmol-2020-316475. Review.
Eighteen-year prospective audit of LASIK outcomes for myopia in 53 731 eyes.
Chua D, Htoon HM, Lim L, Chan CM, Mehta JS, Tan DTH, Rosman M.
Br J Ophthalmol. 2019 Sep;103(9):1228-1234.
Analysis of cases and accuracy of 3 risk scoring systems in predicting ectasia after laser in situ keratomileusis.
Chan C, Saad A, Randleman JB, Harissi-Dagher M, Chua D, Qazi M, Saragoussi JJ, Shetty R, Ancel JM, Ang R, Reinstein DZ, Gatinel D.
J Cataract Refract Surg. 2018 Aug;44(8):979-992.
Conventional Versus Accelerated Collagen Cross-Linking for Keratoconus: A Comparison of Visual, Refractive, Topographic and Biomechanical Outcomes.
Woo JH, Iyer JV, Lim L, Hla MH, Mehta JS, Chan CM, Tan DT.
Open Ophthalmol J. 2017 Aug 29;11:262-272
Postoperative ocular higher-order aberrations and contrast sensitivity: femtosecond lenticule extraction versus pseudo-small incision lenticule extraction.
Tan DK, Tay WT, Chan C, Tan DT, Mehta JS
J Cataract Refract Surg 2015; 41:623-35.
Validation of an objective scoring system for forme fruste keratoconus detection and post-LASIK ectasia risk assessment in Asian eyes
Chan C, Ang M, Saad A, Chua D, Mejia M, Lim L, Gatinel D
Cornea 2015;34(9):996-1004.
Patient and surgeon experience during laser in situ keratomileusis using 2 femtosecond laser systems.
Hall RC, Rosman M, Chan C, Tan DT, Mehta JS.
J Cataract Refract Surg. 2014 Mar;40(3):423-9.
Comparative analysis of two femtosecond LASIK platforms using iTRAQ quantitative proteomics.
D’Souza S, Petznick A, Tong L, Hall RC, Rosman M, Chan C, Koh SK, Beuerman RW, Zhou L, Mehta JS.
Invest Opthalmol Vis Sci 2014; 55:3396-402.
Prevalence and viral load of oncogenic human papillomavirus (HPV) in pterygia in multi-ethnic patients in the Malay Peninsula.
Chong PP, Tung CH, Rahman NA, Yajima M, Chin FW, Yeng CL, Go ES, Chan CM, Yawata N, YamamotoN.
Acta Ophthalmol 2014; 92:e569-79.
Refractive lenticule extraction: transition and comparison of 3 surgical techniques
Ang M, Mehta JS, Chan C, Htoon HM, Koh JC, Tan DT.
J Cataract Refract Surg 2014; 40:1415-24
Incidence and management of suction loss in refractive lenticule extraction
Wong CW, Chan C, Tan D, Mehta JS
J Cataract Refract Surg 2014; 40:2002-10
Comparison of corneal sensitivity, tear function and corneal staining following laser in situ keratomileusis with two femtosecond laser platforms.
Petznick A, Chew A, Hall RC, Chan CM, Rosman M, Tan D, Tong L, Mehta JS.
Clin Ophthalmol. 2013;7:591-8.
Comparison of efficacy and safety of laser in situ keratomileusis using 2 femtosecond laser platforms in contralateral eyes.
Rosman M, Hall RC, Chan C, Ang A, Koh J, Htoon HM, Tan DT, Mehta JS.
J Cataract Refract Surg. 2013 Jul;39(7):1066-73
Visual outcomes comparison of 2 femtosecond laser platforms for laser in situ keratomileusis.
Ang M, Mehta JS, Rosman M, Li L, Koh JC, Htoon HM, Tan D, Chan C.
J Cataract Refract Surg. 2013 Nov;39(11):1647-52.
Severe vernal keratoconjunctivitis requiring trabeculectomy with mitomycin C for corticosteroid-induced glaucoma
Ang M, Ho CL, Tan D, Chan C
Clin Experiment Ophthal 2012 May-Jun;40(4):e149-55
Refractive lenticule extraction flap and stromal bed morphology assessment with anterior segment optical coherence tomography
Tay E, Li X, Chan C, Tan DT, Mehta JS
J Cataract Refract Surg 2012 Sep:38(9):1544-51
Steroid-induced ocular hypertension in Asian children with severe vernal keratoconjunctivitis
Ang M, Ti SE, Loh R, Farzavandi S, Zhang R, Tan D, Chan C
Clin Ophthalmol 2012;6:1253-8
Comparison of eye-tracking success in laser in situ keratomileusis after flap creation with 2 femtosecond laser models.
Luengo Gimeno F, Chan CM, Li L, Tan DT, Mehta JS
J Cataract Refract Surg 2011 Mar;37(3):538-43
A 10-year prospective audit of LASIK outcomes for myopia in 37 932 eyes in a single institution in Asia
Yuen LH, Chan WK, Koh J, Mehta JS, Tan DT, SingLASIK Research Group
Ophthalmology 2010 Jun;117(6):1236-44
Emerging prevalence of microsporidial keratitis in Singapore. Epidemiology, clinical features and management.
Raymond S Loh, Cordelia ML Chan, Seng Ei Ti, Li Lim, Kian Sing Chan, Donald TH Tan
Ophthalmology 2009;116:2348-53
Giant cell arteritis (temporal arteritis) and a case from Singapore
JF Cullen, Cordelia Chan, KL Chuah
Singapore Med J 2003 Jun;44(6):306-8
Microsporidial keratoconjunctivitis in healthy individuals: A case series
Cordelia ML Chan, Julian TS Theng, L Lim, Donald TH Tan.
Ophthalmology 2003;110(107):1420-5.
Ocular surface changes in pterygium
Cordelia ML Chan, Yan Ping Liu, Donald TH Tan.
Cornea 2002;21(1):38-42
Microsporidial keratoconjunctivitis in a healthy contact lens wearing individual without Human Immunodeficiency Virus infection.
Julian TS Theng, Cordelia Chan, Moi Lin Ling, Donald Tan.
Ophthalmology 2001;108(5):976-8
Vascular patterns in pterygium and conjunctival autografting: A pilot study using indocyanine green anterior segment angiography
Cordelia ML Chan, Paul TK Chew, Zainah Alsagoff, Jun Shyan Wong, Donald TH Tan.
Br J Ophthalmology 2001;85(3):350-3
Conjunctival rotational autograft for pterygium
Aliza Jap, Cordelia Chan, Li Lim, Donald TH Tan
Ophthalmology 1999;106:67-71
Surgical management of upper lid epiblepharon
Chai-Teck Choo, Kee-Siew Fong, Cordelia ML Chan.
Eye 1998;12:623-6
Penetrating keratoplasty in the Singapore National Eye Centre and Donor Cornea Acquisition in the Singapore Eye Bank
CML Chan, TY Wong, SM Yeong, TH Lim, DTH Tan.
Annals Academy of Medicine Singapore Jul 1997;26(4):395-400
Changing Indications for penetrating keratoplasty; A newly developed country’s experience
TY Wong, C Chan, L Lim, TH Lim, DTH Tan.
Aust NZ J Ophthalmol 1997;25:145-150
Posterior scleritis
Cordelia ML Chan, Ang Chong Lye
Asia-Pac Journal of Ophthal Jan 1994;6(1):31-3
  • Management of pterygium.
  • Donald Tan, Cordelia Chan
  • Cornea (Third Edition), Krachmer, Mannis and Holland